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​DR CHETTY’S 8TH DAY THERAPY FOR COVID-19

This one-pager summarizes the therapy adopted by Dr Shankara Chetty, from South Africa, to help prevent COVID-19 from progressing towards severe disease. The document focuses on the 8th day onwards of COVID-19, i.e. the inflammatory phase. It does not cover the initial viral phase, for which early treatment protocols already exist and can be prescribed before. The document is for information only, not for therapeutic advice. If you catch COVID-19, please seek immediate medical help.

The 8th Day Therapy aims at mitigating a possible hypersensitivity reaction, that can trigger an inappropriate immune response, including a possible subsequent cytokine storm. This transition from the initial viral phase typically occurs on Day 8 after the first symptoms. It’s essential for the treating physician to establish as precisely as possible the first day of symptoms, to alert the patient of the date when a possible sudden aggravation of symptoms may occur. Shortness of breath is typically associated with this aggravation.

The 8th Day Therapy encompasses 4 distinct interventions. They sometimes follow a previously prescribed early treatment protocol. Possible drug interactions need to be carefully assessed.

Intervention #1: Corticosteroids
Goal: To stop the hypersensitivity reaction, to stop the release of mediators and to prevent an inappropriate immune response, including a possible subsequent cytokine storm.
Medication: Prednisone 80 mg dly x 1 week.
Note: Increase dose rapidly to get symptomatic relief quickly. CRP and IL6 values must show quick decline. Dose will vary according to variants and severity of reaction. Can go as high as 100 mg tds for first few days. Wean off cautiously when CRP and IL6 are normal or patient is well for a few days. Those with prolonged reactions are difficult to wean, so consider adding Azathioprine 50mg dly to decrease steroid requirements.

Intervention #2: Anti-histamines
Goal: To clear the histamines that have been released.
Medications:
H1: Promethazine 25 mg tds x 5 days or Levocetirizine 5mg bd x 1 month to follow Promethazine
H2: Cimetidine 400mg x 1 month or another H2 blocker Other anti-histamine drugs can be suitable

Intervention #3:Anti-leukotrienes
Goal: To clear the leukotrienes that have been released.
Medication:
Montelukast 10 mg bd x 5 days then dly x 1 month

Intervention #4: Blood Thinners
Goal: to clear platelet activating factors.
Medications:
Aspirin 325 mg dly x 1 month. Add Xarelto 15 mg bd if D.Dimer is raised; decrease to 15 mg dly x 1 month once D.Dimer is normal

Optional Interventions
  • Add appropriate antibiotics for those with fever, bacterial co-infection or raised Procalcitonin levels
  • Add Venteze syrup PRN for those suffering from asthma
  • Add Ivermectin 12 mg dly x 5 days in those with cough, dyspnea or decreased oxygen saturation
  • Fluvoxamine may be a suitable drug, yet Dr Chetty has so far no experience with it.

By Dr Shankara Chetty, MD, with the editorial assistance of JP Kiekens / covexit.com Strictly for Information Only, Not for Medical advice. Version of May 12 2021. For any questions, please use this form.
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  • Journey
    • My Health >
      • Genome
      • ACC Fight
    • Chris' Journey
    • About me >
      • Personality
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  • Index
  • Basics
    • Discussions by Subject >
      • A-I >
        • Acidity
        • Agriculture
        • Anti-nutrients
        • Antioxidants
        • Brain - Key to Keto-Adaptation
        • Carnivory >
          • Carnivore Science Video
          • My Carnivore Experiment Lecture
        • Cholesterol
        • CICO
        • Coffee
        • Dental >
          • Dental Caries and Carbohydrates
        • Deuterium
        • Dietary vs Liver made fats
        • Fiber >
          • Fiber Menace
        • Gluten
        • Honey
        • Immunity
        • Insulin Resistance
      • J-Z >
        • Ketosis
        • Light and Health
        • Methylation
        • Mitochondria
        • Nutrients >
          • Minerals
          • Carbohydrate >
            • Glucose
          • Fat >
            • Saturated Fat
          • Protein >
            • Protein Leverage Hypothesis
          • Nutrients - Plant vs Animal Sources
          • Potassium
        • Obesity
        • Salt gets its own page
        • Soy - Western A. Price
        • Statins
        • Uric Acid
        • Vaccines
        • Vegetarianism >
          • Vegetarians Have Smaller Brains
        • Vitamins >
          • D
          • Vitamin C
          • Vitamin D >
            • Covid19-D
            • Slides from Garland's Lecture
          • Vitamin K
    • Foods - Nobody does it better than Georgia Ede >
      • Arachidonic Acid
      • Beef >
        • Red meat - health concerns
      • Meat Composition
      • Vegetables
    • The People >
      • Vilhjálmur Stefánnson
      • Benjamin Bikman
      • Ivor Cummins
      • Georgia Ede MD
      • Phil Escott >
        • Arthritis: The Best Thing That Happened To Me
        • Pure Activity
      • Duane Graveline (SpaceDoc)
      • Barry Groves >
        • Do You Have to be Mental to be a Vegetarian
      • Zoe Harcombe
      • Adele Hite
      • Lierre Keith
      • Hugh Khan
      • Malcolm Kendrick
      • Paul Mabry
      • Malaena Medford >
        • MM On Calories
        • MM On Cancer
        • MM on Covid
        • MM On Feeding Our Young
        • MM On Histamine
        • MM On Ketosis
        • MM On Peanuts
        • MM On Raw Food
        • MM On Sustainability of Food
      • Tom Naughton - Fat Head
      • Tim Noakes
      • L. Amber O'Hearn
      • The Bear - Owsley Stanley
    • Rosedale Lecture
    • All Sorts of Links and Videos
    • The 20 Myths
    • Diet and Nutrition for the Australian People
    • Diet, Nutrition and Biochemistry Blogs and Websites
    • Discussion on the 'life expectancy' myth
    • Micronutrients Veg vs. Meat
    • Human History >
      • Articles
      • Catching Fire
      • How Carnivorous are we
    • The Fat of the Land
  • Diseases
    • Aging
    • Arthritis
    • Cancer >
      • Cancer as a Metabolic Disease
      • Cancer - General
      • Cancer - Breast
      • Cancer - Colon >
        • Cancer - Colorectal (links)
      • Cancer - Pancreatic
      • Cancer Skin >
        • Cancer - Skin - SecondOpinions
      • Carbohydrate and Cancer
    • Covid19 >
      • Antivirals
      • Chetty
      • Covidvax
      • Mask
    • Cramp
    • Dementia
    • Diabetes
    • Diverticulosis >
      • Diverticular Disease Information - Barry Groves
    • Fatty Liver
    • Gallstones
    • Gout
    • Heart Disease
    • Kidney Stones
    • Psychological
    • Scurvy
    • Ulcerative Colitis
  • The Studies
    • Of mice and men
    • Links to Studies (and Other Knowledge)
    • The Study
    • Uffe Ravnskof Commentary
    • 8 Glasses of Water a Day?
    • Simple Facts
    • To Microwave or Not to Microwave
    • Social Stuff >
      • Political Party Policies On Food Guidelines
    • Gun Stuff >
      • Shooting
    • Climate Science >
      • 97%
      • David Kear Booklet
      • 31000
      • Gerlach-1991
      • Alarmist Claim Rebuttals
  • Tools
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  • Blog
    • BUPA >
      • Bupa "Consultation" Documents
    • Greggatshack's Wordpress Blogs
    • Blogs from Malaena Medford
    • Various and Sundry >
      • My Session with Savelev >
        • Steak
      • My Session With Blocked By Pete Evans
      • Fencing Manual
      • Vic Stone and I on handicapping
      • Betty Megaw
      • Chris Genealogy Test
  • Quotes
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  • Articles
    • 42
    • The Cure for Diabetes - Men's Health
  • Contact
  • RDA
    • A-Z of Food
  • Liver Flush
  • Smacking
  • Controversy
    • Controversy-Kathleen
    • SatFat
    • WTFWR
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  • IQ
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